Vitamin K2 + D3 5000 IU Supplement with Calcium & BioPerine. Maximum Absorption. Supports Healthy Heart, Bones & Teeth. Powerful Immune System, Energy & Mood Enhancer. No Fillers, Gluten-Free Capsules

NutriRise Vitamin K2+D3 contains:

- 5,000 IU of vitamin D3 (cholecalciferol)
- 100mcg of vitamin K2 (Mk-7)
- 210mg of calcium (calcium carbonate)
- 5mg of BioPerine (black pepper fruit extract). 

Our Vitamin D3 + K2 supplement is non-GMO and made with all natural ingredients. It is free of gluten, dairy, artificial preservatives, harmful binders and fillers, artificial colors, and flavors. Our capsules are made of cellulose, not gelatin, the perfect choice for vegetarians and vegans, or those allergic to gelatin.
Our Vitamin D3 + K2 blend contains only the active ingredients to support your body and nothing extra that you don’t need!

Customer safety is our highest priority. That's why all of our supplements are manufactured in an FDA-Registered, GMP-Certified facility in the United States. And we take testing seriously. All of our products are tested four times throughout our supply chain. Once, when we receive raw ingredients, again during manufacturing, with further testing on finished products. Finally, products are third-party tested by an unbiased, independent organization. This approach ensures our products meet exacting specifications, and that they’re safe. All raw materials and finished products are tested in the United States.

Unlike single vitamin supplements, our product is carefully crafted with your overall health in mind. Instead of providing just vitamin D3, we paired it with K2 so that when D3 increases your body’s absorption of calcium, vitamin K2 steps in and directs the calcium, telling it exactly where to go. We added calcium to increase your daily intake, and BioPerine to provide an extra boost for all three nutrients, allowing your body to absorb them and begin utilizing them immediately. Our supplement is like a complete little gift for your body, packaged and ready to go!

Vitamins K2 and D3 are both fat-soluble vitamins, and calcium carbonate requires stomach acid for absorption. Take this supplement with a meal containing some dietary fat for best absorption. Do not take it on an empty stomach.

Vitamin D3 is the same form of vitamin D our skin absorbs from the sun. Considered more bioavailable than vitamin D2, D3 is a powerhouse for our bones, cardiovascular system, skin, hair, nails, and immune system. One of vitamin D3’s primary roles is helping increase calcium absorption within the intestines. Vitamin D3 has been shown to raise vitamin D levels in the blood more quickly and efficiently than vitamin D2.

We use vitamin K2 in the form of Mk-7 in our supplement because this type stays in the body longer and has more time to exert a positive impact on the body than other forms of vitamin K2. Vitamin K2 works synergistically with vitamin D3 to distribute calcium to the appropriate places within the body. Without K2, calcium may end up in arteries, soft tissues, even breaking down the elastin of the skin. Adding vitamin K2 to our supplement helps ensure that the calcium is directed appropriately to the bones and teeth. The goal is solid bones and soft blood vessels, not the other way around!

Calcium carbonate contains larger amounts of elemental calcium than the alternative form of calcium, calcium citrate. Vitamin D3 allows the intestines to absorb more calcium, so including it in this supplement provides a boost to your daily intake, providing an immediate source of this vital mineral for bone health.

BioPerine, or black pepper fruit extract, is added to our supplement to enhance the bioavailability of the other nutrients. Just 5mg of BioPerine works to improve the bioavailability of vitamin D3, vitamin K2 and calcium! Essentially, BioPerine increases the body’s metabolism and creates an increased demand for these nutrients, thus allowing the body to absorb and utilize them more readily. 

In terms of your overall health, vitamins D3 and K2 are a power-packed duo who work best together! Over 1 billion people worldwide experience vitamin D deficiency, and unfortunately supplementing with this product alone can lead to calcium deposits in arteries and soft tissues, exactly where the calcium doesn’t belong. However, pair it up with K2 and you’ve got a match made in heaven! The combination of vitamins D3 and K2 may:

- Support bone health by depositing calcium and phosphate in your bones and aiding in bone healing through a chemical reaction known as carboxylation.

- Support joint health by directing calcium into bones and supporting a healthy inflammatory response.

- Support robust and stable moods and overall outlook on life.

- Support cardiovascular health by redirecting calcium deposits into bones instead of soft tissues, organs, and blood vessels.

- Promote healthier hair, skin, and nails by supporting healthy hair follicles and elastin within the skin.

- Promote a healthy immune system by filling vitamin d receptor sites within the immune system, allowing proper chemical reactions to take place to support and regulate the immune system.

- Support a healthy gut by helping maintain healthy gut bacteria levels.

- Promote insulin sensitivity and blood sugar regulation.

- Support healthy sleep.

Vitamin D3 helps our bodies to absorb calcium and phosphate. Once it does, Vitamin K2 can go to work and ensure that those minerals end up in the right place (our bones!) instead of in our arteries where calcification and plaque build-up causing heart disease, heart attacks, and ultimately premature death.

Vitamin K2 is generally well tolerated by most people, and is commonly found in many foods, especially green leafy vegetables. However, side effects are possibly, though uncommon.
These include:

- Decreased appetite
- Shortness of breath
- Swelling
- Irritability
- Paleness
- Yellowing of the skin and eyes
- Low blood pressure

If any of these occur, discontinue use and contact your doctor immediately.

The primary reason for taking a Vitamin K2 + D3 supplement is to raise low vitamin D levels. Over 1 billion people worldwide suffer from vitamin D deficiency. This number includes up to 40% of American’s. The National Institute of Health recommends levels 50nmol/L or higher for healthy individuals. The blood test for this measurement is the Serum 25-Hydroxyvitamin D [25(OH)D. This test measures levels after the liver processes the vitamin D, but before the activation by the kidneys. Measuring this level is considered most accurate because its levels remain consistent in the bloodstream for approximately 15 days, whereas levels after it activates in the kidneys, can fluctuate within a few hours. 

Symptoms of low vitamin D include:

- Mood changes
- Bone loss
- Muscle cramps and weakness
- Bone and joint pain
- Fatigue

Supplementing with a Vitamin D3 supplement for low vitamin D3 levels is shown to raise blood levels more than supplementing with D2. A study in The Journal of Clinical Endocrinology & Metabolism featuring 38 adults with low levels (<30ng/ml) of vitamin D showed the clear winner of D3 over D2 in the controlled study. Surprisingly, many of the prescriptions written for vitamin D supplementation are in the form of vitamin D2. The body’s activation of D3 into the usable form takes considerably longer in the liver than the activation of D2. This is the reason D3 is more effective at raising levels in the blood, simply because of the length of time it remains in circulation.

Vitamin D deficiency increases with age. Older adults produce four times less vitamin D than young adults in their early 20’s. There are a variety of factors that contribute to this happening, though the largest is a decrease in kidney function. The reduction in our body’s vitamin D production with age directly corresponds to a host of other chronic conditions. These include osteoporosis, due to the body’s inability to absorb adequate calcium, and cardiovascular disease, resulting from calcium deposits in inappropriate and unhelpful areas of the body.

Supplementing with Vitamin D3 alone will cause the intestines to increase the absorption of more calcium and phosphate, which we all know is good for the bones. Both are minerals necessary for healthy bones and teeth. Vitamin D3 activates proteins called osteoclasts which help with bone healing. 

Multiple clinical studies exist investigating a link between vitamin D and depression. A definite correlation exists between low levels of vitamin D and depression. One study showed higher levels of depression in individuals with lower levels of vitamin D in their blood. Another study featuring a group of overweight patients, both with a diagnosis of depression and those without, showed improvements in depression with vitamin D supplementation. In this study, those with higher levels of vitamin D experienced more substantial gains in their depression than individuals with mild depression. Also, vitamin K2 is shown in animal studies to not only relieve symptoms of depression but anxiety as well.

Supplementation with Vitamin D3 and K2 have been shown in clinical studies to have a positive impact on the health of hair, skin, and nails. Vitamin D has been shown in studies to impact hair loss positively. Although it isn’t thoroughly understood, scientists believe that it works on the follicle itself, in a sense acting as if to wake up the sleeping follicle. One particular type of hair loss, or balding, known as alopecia areata, shows lower levels of vitamin D in test subjects with this diagnosis. Individuals without this form of alopecia had higher levels of vitamin D in their blood, almost 10ng/dL more! While not necessarily a cure for alopecia, it is one additional piece of the puzzle worth investigating, especially since we’ve shown that adequate levels of vitamin D are involved in so many other critical processes within our bodies!

Studies show that lower levels of vitamin D correspond with weaker immune systems. When vitamin D activates within the body, a chemical known as cathelicidin is produced which has antimicrobial properties, thus killing bacteria and viruses. This is like having your own internal pharmacy, dispensing antibiotic and antiviral medications on your behalf! Our entire immune system contains vitamin D receptors, so when our blood levels are adequate, these receptors fill and a stronger immune system results. Vitamin K2 also appears beneficial in overall immune regulation in clinical trials, but the reason is unknown.

Studies have also shown that individuals with overactive immune systems, such as the case with any autoimmune disease, have lower levels of vitamin D than people without such a diagnosis. Our immune systems require a delicate balance. When they aren’t strong enough, our bodies are at risk of contracting any infection that comes along. When they are overactive, they begin to see our own bodies as the enemy, and they attack our own healthy cells and autoimmune diseases emerge. One study indicated that vitamin D helps to regulate our immune system, telling it what to do and how. A deficiency contributes to the immune response weakening or even attacking cells that aren’t a danger to our health.

Supplementation of D3 and K2 helps provide the body with two critical components for our overall immune health. It’s like having a fully staffed pharmacy, working on your behalf. When these two vitamins are deficient, other parts of the immune system have to work overtime and the system gets weaker, allowing a sickness to take over and before you know it, you're in bed with a fever and chills. In other people, deficiency may lead to the immune system going in the other direction and mounting an attack on its own body. Either way, immune health is compromised and illness begins. The best course of action is to have your levels checked from time to time and maintain levels of 25(OH)D at 50nmol/L or higher for optimal immune health.

In regards to type 2 diabetes mellitus, vitamin K2 is the champion in this match. Clinical trials show that vitamin K2 not only increased insulin sensitivity, but it also helped regulate blood sugar levels as well. Interestingly, the same mechanism that helps direct calcium into the bones, osteocalcin, is responsible for the improvements in insulin resistance and an overall improvement in blood sugar control. Diabetes is also known to have an inflammatory action within the body and as previously demonstrated, K2 and D3 have a positive impact on reversing the inflammatory response within the human body.

Overall increased insulin sensitivity means that our bodies can pull glucose out of the bloodstream and use it in our cells for energy. When our bodies become desensitized to insulin, our cells don’t recognize it as the gatekeeper for glucose, so glucose stays in our bloodstream, resulting in high blood sugar levels, and decreased energy within the cells. If blood glucose becomes high enough, the person will fall into a coma and eventually die because the glucose is in the wrong place and isn’t able to be utilized for energy. Maintaining insulin sensitivity is vital in this process because cells have to allow insulin to pull glucose into the cells and out of the blood, and vitamin K2 helps to do this. This regulates our blood sugar levels and helps with overall control of diabetes.