Your immune system consists of a vast network of organs, cells, proteins, and chemicals that should work together 24/7 to protect you from foreign invaders like bacteria, viruses, parasites, fungi, and even mutating cells, as seen in cancer! A healthy immune system will also recognize and neutralize harmful substances from your environment.

The immune system is activated when it recognizes something that isn’t “self.” Specific proteins on the surface of microbes called antigens attach to special receptors on immune cells, triggering a series of processes to protect you by deploying lymphocytes (white blood cells), upregulating inflammation temporarily, and even increasing body temperature (i.e., fever!). 

Suppose this is the first time your body has had contact with this specific disease-causing microbe. In that case, it stores information or “memory” about it to ensure you can fight it more effectively next time - this is called the adaptive immune response and is how the proteins known as antibodies are produced. [2]

The more active the immune system, the better, right? Not always. A healthy immune response is a delicate balance between fighting off foreign invaders to protect the body from harm and avoiding an “over-response” which may damage the body’s tissues, as seen in autoimmune conditions like rheumatoid arthritis and Hashimoto's thyroiditis. Autoimmune disorders affect around 5-8% of the US population, with prevalence steadily increasing [3].

Luckily, some incredible natural compounds act as “immunomodulators” by helping to balance the immune response.

A healthy immune system needs various nutrients to function optimally, such as zinc, iron, vitamin c, vitamin d, selenium, and folic acid. Antioxidants are also essential since they help neutralize damaging free radicals produced during an immune response. [4]

Amazingly gut health is another non-negotiable for a healthy immune response since around 70% of the human immune system resides in the GI tract! [5]

How does low immunity affect the body?

Let’s dive a little deeper into some warning signs that your body may share with you when your immune system isn’t running optimally.

Signs of a weak immune system*

*Please note: It’s always important to discuss any concerning symptoms with your primary healthcare practitioner. 

Do any of these sound familiar? Chances are, your natural defenses might need some help. We’ve developed a range of premium dietary supplements bursting with essential vitamins, minerals, antioxidants, and other natural compounds to keep your immune system strong and balanced all year round. Let’s take a look at them!

Understanding the immune support supplements

Super Immunity Complex

Nutrient status, antioxidant defenses, and gut health are vital for a well-rounded immune system. Our Super Immunity Complex supplement is packed with 10 high-potency ingredients, including essential vitamins like Vitamin C, Vitamin E, and Vitamin B6, plus Zinc, powerful herbs, and probiotics that support a healthy immune function.

Symptoms that Super Immunity Complex may support:

• Frequent colds and flu
• Slow wound healing
• Oxidative stress
• Imbalanced inflammatory processes
• Fatigue
• Seasonal allergies

What does the research say?

A randomized, double-blind controlled trial found that supplementing with Vitamin C at 50 mg per day (Super Immunity Complex contains 270mg of Vitamin C!) experienced a reduced duration of the common cold in comparison to those taking less than 50 mg of Vitamin C. [8]

A meta-analysis of randomized controlled trials focused on the efficacy of elderberry on upper respiratory infections. Researchers found that supplementation with elderberry could significantly reduce upper respiratory symptoms compared to a placebo. [9]

Another randomized placebo-controlled trial looked at the effect of garlic on immune cells and cold/flu symptoms. At the end of the study, those taking garlic had a significant increase in the proliferation of natural killer cells and T cells and reduced severity of cold/flu symptoms compared to the placebo! [10]

Ashwagandha Capsules & Ashwagandha Gummy +

Did you know that stress can reduce the number of immune cells your body has on hand to fight off invaders? Ashwagandha is famous for its natural stress-relieving properties, which could help to explain its potentially positive effects on immunity. You can choose from Ashwagandha capsules or our delicious gummies, which contain two additional immune-boosting nutrients… Vitamin D and Zinc!

Symptoms that Ashwagandha may support:

• Stress & anxiety
• Fatigue 
• Low mood

What does the research say?

Most research focuses on the remarkable adaptogenic properties of Ashwagandha, which could help reduce low immunity induced by chronic stress. For example, a randomized controlled trial found that eight weeks of Ashwagandha supplementation significantly reduced cortisol levels and other stress assessment scales. [11]

Vitamin K2 + D3 Complex & AdaptoZen Vitamin D3 + K2 Drops

Vitamin D, also known as the sunshine vitamin, is one of the essential nutrients for immune support (and overall health). However, it’s thought over 40% of Americans may suffer from vitamin d deficiency. To boost and maintain vitamin d levels quickly, we offer two specialized immune system supplements focusing on Vitamin d. Vitamin K2 + D3 capsules or new AdaptoZen Vitamin D3 + K2 Drops are formulated for enhanced absorption with K2 for safe calcium transport within the body. 

Symptoms that Vitamin D3 + K2 may support:

• Low immunity
• Respiratory symptoms
• Fatigue
• Low mood
• Joint discomfort

What does the research say?

A meta-analysis of randomized controlled trials found that supplementation with Vitamin D significantly reduced the risk of respiratory tract infections. [12]

It’s thought that Vitamin D also acts as an “immunomodulator,” helping to regulate immune function and prevent an overresponse [13]. For example, research shows that a low intake of Vitamin D is associated with a higher risk of certain autoimmune conditions like rheumatoid arthritis. [14]

Alongside Vitamin D, Vitamin K also plays a vital role in immune function by acting as a cofactor for specific proteins that can impact how immune cells function. [15]

Turmeric With Ginger

In traditional medicine paradigms, turmeric and ginger have long been used as immune support tonics, with research now revealing their powerful antioxidant and anti-inflammatory properties. Our Turmeric with Ginger is standardized to 95% curcumin with BioPerine for maximized absorption.

Symptoms that Turmeric & Ginger may support:

• Low immunity
• Respiratory symptoms
• Inflammation
• Occasional pain
• Digestive discomfort

What does the research say?

While the use of turmeric and ginger for immune support is mainly based on anecdotal evidence, more focused research on the mechanisms of these super spices gives insight into how they may assist with immune health.

For example, a meta-analysis of randomized controlled trials found that curcumin supplementation had the potential to significantly raise total antioxidant capacity, which can help neutralize damaging free radicals produced during immune responses. [16]

Another meta-analysis on ginger found that it too may raise total antioxidant capacity while also reducing inflammatory markers like C-reactive protein. [17]

Apple Cider Vinegar Capsules & Gummies

In folk medicine practices, Apple cider vinegar has long been used as a traditional immune support remedy for flu and colds. Many people struggle to add apple cider vinegar to their regimen due to the strong smell and taste. We’ve got you covered with convenient Apple Cider Vinegar capsules or delicious gummies.

Symptoms that Apple Cider Vinegar may support:

• Colds/flu
• Indigestion
• Blood sugar spikes/crashes
• Stubborn weight gain

What does the research say?

Apple cider vinegar for immunity is mainly based on anecdotal evidence. Some researchers think that the probiotic and polyphenol content of apple cider vinegar is what provides immune support benefits. [18]

Black Elderberry Gummies & Elderberry Tincture With Vitamin C

For thousands of years, black elderberry has been one of the most sought-after immune-boosting herbs. Bursting with antioxidants, phytochemicals, Vitamin C, and other unique nutrients that help stimulate your immune system, our Elderberry Gummies and Elderberry Tincture with Vitamin C are incredibly effective ways to support your body’s natural line of defenses.

Symptoms that Elderberry may support:

• Low immunity
• Frequent colds/flu
• Respiratory symptoms
• Oxidative stress
• Inflammation

What does the research say?

A randomized controlled trial found that elderberry supplementation significantly reduced the duration and severity of colds in travelers. [19]

A meta-analysis of randomized controlled trials found that elderberry supplementation was associated with reduced symptoms in those with upper respiratory tract infections. [20]

A randomized, double-blind controlled trial found that supplementing with Vitamin C at 50mg per day experienced a reduced duration of the common cold in comparison to those taking less than 50mg of Vitamin C. [8]

Mushroom Nootropic Gummy +

Mushrooms are thought to act as potent immunomodulators to balance and strengthen the immune response and support healthy inflammatory processes. Our Mushroom Nootropic Gummy + is packed with 10 great mushrooms, including immune-boosting Reishi, Shiitake, and Turkey Tail.

Symptoms that Mushroom Gummies may support:

• Low immunity
• Fatigue
• Suboptimal gut health
• Poor memory/focus
• Brain fog

What does the research say?

A randomized dietary intervention in healthy young adults found that consuming shiitake mushrooms daily significantly increased immune cell proliferation and activation. [21]

A study on human cells found that Reishi extracts modulated both immune and inflammatory pathways. [22]

AdaptoZen Superfood Greens

Our groundbreaking AdaptoZen Superfood Greens powder provides 47 plant-powered ingredients offering essential vitamins, minerals like zinc, antioxidants, probiotics, and phytonutrients to help your immune system thrive! It also contains a targeted immunity-boosting blend with echinacea, astragalus, and mushrooms for maximum support.

Symptoms that Adaptozen Superfood Greens may support:

• Frequent colds/flu
• Low immunity
• Respiratory symptoms
• Inflammation & oxidative stress
• Bloating & irregularity
• Stress

What does the research say?

A meta-analysis of experimental studies examined the use of Echinacea in the common cold. Researchers found that echinacea supplementation significantly reduced the likelihood of catching a clinical cold by up to 55% compared to placebo. [23]

Chlorella is not only rich in zinc, but a randomized controlled trial found that healthy adults who supplemented with this super green had a significant increase in natural killer cell activity - an important indicator of immune function. [24]

A double-blind, placebo-controlled trial found that supplementation with probiotics could significantly reduce cold/flu symptoms, incidence, and duration in children compared to placebo. [25]

Black Seed Oil

Our Black Seed Oil is cold-pressed to ensure the highest quality. It contains a potent health-boosting compound known as thymoquinone, which can act as an immunomodulator alongside powerful antioxidant and anti-inflammatory properties that may help fight the damaging free radicals produced during an immune response.

Black Seed Oil may support:

• Overall immunity
• Inflammation & oxidative stress
• Respiratory health
• Cardiovascular wellness
• Skin & brain health

What does the research say?

Researchers found that after healthy individuals supplemented with black seed, they saw a significant increase in immune cells responsible for rapidly killing invading microbes. [26]

A randomized controlled trial examined the effects of black seed on inflammation and oxidative stress markers in those with the autoimmune condition rheumatoid arthritis. At the end of the study, they found that black cumin seed significantly increased levels of IL-10, which is an anti-inflammatory chemical in the body that helps balance immune responses. [27]

Research shows that thymoquinone, one of the active constituents of black seed, could help support antioxidant enzymes in the body, which may help to promote immunity and fight free radicals. [28]

Irish Sea Moss Complex

Seaweed is the ocean's superfood, bursting with vitamins, antioxidants, and minerals like zinc and iodine that your immune system loves. Iodine is vital to optimal thyroid function, one of seaweed supplements' most notable health benefits. Balanced thyroid hormones and correct functioning have a powerful impact on the body's overall health and chemical processes.

Our Irish Sea Moss Complex contains wildcrafted seaweed and burdock root for additional support and total body nourishment!

Symptoms that Irish Sea Moss Complex may support:

• Fatigue & low energy
• Thyroid health
• Weakened immunity
• Sluggish detoxification
• Inflammation

What does the research say?

Research in animals shows that Irish sea moss may help to improve immune modulation and gut health due to its rich prebiotic fiber content. [29]

Scientific evidence examining Irish sea moss and immunity in humans is still lacking. Still, it’s hypothesized that its immune support benefits are primarily derived from its antioxidant and nutrient content and its prebiotic fiber content.

For example, a meta-analysis of randomized trials found that zinc supplementation could reduce the incidence of acute respiratory infections in children. [30]

Final Thoughts

We hope this article has left you feeling more empowered to take control of your immunity by helping you make the right NutriRise supplements choice based on your unique needs!

If you have any questions, please feel free to reach out to our customer advocate team at hello@nutririse.com!

Note: This article is for informational purposes only and not intended for use as medical advice. Always consult your healthcare provider before starting any dietary supplements.